Verses 1-4 describe an overwhelming sense of God's glory and the appropriate response to it. On a throne. A high and lofty throne. So large that just the hem of his robe fills the temple. Heavenly beings attend him. They sing, "Holy, holy, holy is the Lord of hosts."
Verses 5, in contrast, describes the great contrast with this glory with the human condition. Isaiah realizes that he is unworthy.
Verses 6-7 give us reassurance. Since we are not worthy, God has a way of redeeming us, of overcoming our sin. Isaiah's guilt was removed.
Verse 8 reminds us why we need this redemption. We have a task. Isaiah accepted his call.
(much of this from or inspired by Isaiah 1-39, by Walter Brueggeman)
How much of this is repeated in a typical church service?
Do we recognize an overwhelming divine presence?
Do we recognize our own sinfulness?
Can we receive redemption? If so, what are we prepared to do with it?